I hate crowds in general but I love music. I often find that things I dislike can be overcome by things I do like, eg my fear of speaking to a group of people is less than my love of physics so I was able to give a presentation on the different types of Superstring Theories. Similarly, I thoroughly enjoy going to concerts and do so frequently because I like the music more than I hate the crowds, so ultimately only you can know what you will be able to deal with in that situation.
You might want to get seated tickets or stand near the back. I went to Download festival this year, and I was very near to the front for a lot of the acts (Slash, Black Sabbath, Soundgarden, Megadeth, Machine Head, Billy Talent, Skindred, Fear Factory etc so not a calm crowd by any means, there was a lot of pushing and jumping) and I enjoyed the experiences, but my boyfriend (NT but generally doesn't like crowds) preferred being closer to the back which we were for quite a few of the acts, the density of people is at least twice in the first 10 or so rows what it is in about the middle.
One thing that bothered me when I went to my first gig (Motley Crue, so very loud) was having one side of me much louder than the other because I was at the far left of the stage. When I went to see Alice in Chains with my (mild Asperger's) ex, he automatically went to the middle of the stage because he had the same problem and it does actually help if you have an issue with uneven surround sound.
So I guess my advice would be that no one can tell for you whether the disliking crowds/wanting to be there balance is worth it for you, but if you do go you might want to have a centre back seat/standing position, which would also allow you to get in and out last and first respectively so you won't get crushed by the stampede of a moving crowd. Also, if you can go with a really big person!