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Ibuprofen and Acetaminophen soothe my symptoms. why?

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omid
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20 Jan 2015, 10:06 am

Just noticed by chance that ibuprofen or acetaminophen make some of my symptoms disappear.
I have many times had this effect when taking these for other reasons. Frankly I always thought I feel mentally better when I have a cold. Turned out it wasn't the cold but the Ibuprofen or Acetaminophen I took FOR the cold. I tried those without having cold and they work like a charm. I'm not saying they cure my symptoms but they reduce many of the symptom that bother me the most.

Why is this? what do you think? I read Ibuprofen reduces nitric oxide (or whatever) which is elevated in autism.

High nitric oxide production in autistic disorder: a possible role for interferon-gamma.
Ibuprofen: effect on inducible nitric oxide synthase


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Korin
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20 Jan 2015, 12:43 pm

They just soothe my chronic pain.



Korin
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20 Jan 2015, 12:44 pm

It's funny how alcohol soothes my Stims



eggheadjr
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20 Jan 2015, 1:08 pm

I had read an article a while back that said autistic children expereinced a reduction in symptoms when they had a fever.

I don't know if that has anything to do with the topic raised by the OP - maybe it does?

I saw another study a while ago that showed people who are autistic tend to suffer from chronic inflammation. I noted this article as I am monitored by both my doctor and a hematologist for high platelet count of indeterminite origin (which is a sign of chronic inflammation).


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andrethemoogle
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20 Jan 2015, 6:31 pm

I would advise not taking either too much, as they can cause severe damage to your liver (especially Ibuprofen)



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21 Jan 2015, 4:52 pm

omid wrote:
Just noticed by chance that ibuprofen or acetaminophen make some of my symptoms disappear.

Why is this? what do you think?



I think it may just be (other than what was said in those articles) that those medications calm "stuff"----like, when we have a headache, for instance, their job is to calm whatever it is, that causes it (ie, inflammation caused my sinuses); so, it stands to reason, IMO, that other "things" (your ASD symptoms) would ALSO be calmed.

A note about Ibuprofen: You can absolutely POISON yourself with that stuff!! I had a problem with it, and told my doctor, and she agreed with me, when I told her that it could be, like, poison (unfortunately, I can't remember, right now, what it was, that I experienced); but, I wouldn't take it, unless I absolutely HAD TO.



Korin
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21 Jan 2015, 4:54 pm

Campin_Cat wrote:
omid wrote:
Just noticed by chance that ibuprofen or acetaminophen make some of my symptoms disappear.

Why is this? what do you think?



I think it may just be (other than what was said in those articles) that those medications calm "stuff"----like, when we have a headache, for instance, their job is to calm whatever it is, that causes it (ie, inflammation caused my sinuses); so, it stands to reason, IMO, that other "things" (your ASD symptoms) would ALSO be calmed.

A note about Ibuprofen: You can absolutely POISON yourself with that stuff!! I had a problem with it, and told my doctor, and she agreed with me, when I told her that it could be, like, poison (unfortunately, I can't remember, right now, what it was, that I experienced); but, I wouldn't take it, unless I absolutely HAD TO.


Naproxen is worse and in commercials more



Campin_Cat
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21 Jan 2015, 6:50 pm

Korin wrote:
Naproxen is worse and in commercials more

Yeah, I know wha'cha mean.


I just noticed I said "Ibuprofen", when I MEANT to say "Acetaminophen"----that you can absolutely poison yourself, with it!!



Korin
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21 Jan 2015, 7:09 pm

Ibuprofen is good in moderation and I have ulcerative colitis. Naproxen is far worse and makes my throat burn.



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22 Jan 2015, 1:13 pm

I think there may be something in the ibuprofen effect. I took it a couple of times before I knew about AS, just to try and ease out my general feelings of physical discomfort, which were playing up at the time. There was nothing specifically wrong with me except that minor aches, pains and itches had been feeling very amplified and I couldn't screen it all out. I felt better after the tablets, and would take them all the time if I thought it safe, but I don't trust them, so I only use it as a last resort.

That's purely for sensory issues. I haven't noticed any improvement in my social competence, executive function problems, or any other autistic trait. But I haven't particularly looked at those.