We All Live in a Yellow Submarine

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I woke up this morning singing "We all Live in a Yellow Submarine, a Yellow Submarine, a Yellow Submarine."

This is a little unusual because I was in REM sleep (it was a little bit before 4 A.M.) It was trying very hard to communicate with me. So it used the words of a Song to communicate with my daytime brain.



So I began to think this is unusual. What is my REM brain trying to tell me? It must be important.

After thinking for a while, I came to the conclusion that it was unwrapping something very hidden.

A few days ago, I was searching for information using the internet and uncovered something very important. I came across a discussion but it was INVISIBLE. That is very strange. It was a way in which certain individuals could communicate on the Internet, out in the open, but it was invisible to everyone except those who knew how to unwrap it. The technique they used was something I developed around 20 years ago. It is a simple form of Cryptography. That is one of my many skills.

So I am able to unwrap the message it contained. I WILL NOW BRING IT OUT INTO THE OPEN.

China is experimenting on mutant Covid strains again – should we be worried?

Samuel Lovett, Deputy Editor of Global Health Security

Chinese scientists are once again experimenting on mutant coronavirus strains.

Last month, a group of virologists from Beijing cloned and mutated a Covid-like virus found many years ago in a pangolin and used it to infect ‘humanised’ mice.

All eight mice infected with the GX_P2V virus went on to die, sparking doom-laden headlines around the world.

The purpose of the research, the scientists said, was to determine the danger posed to humans by new Covid viruses and provide data for the development of a universal vaccine – one that is capable of protecting against all coronaviruses.

Perhaps unsurprisingly given the controversy surrounding the origins of Covid-19, the study, which has yet to be peer-reviewed, didn’t land well.

Professor Francois Balloux, the director of the UCL Genetics Institute, derided it as “scientifically totally pointless”.

“I can see nothing of vague interest that could be learned from force-infecting a weird breed of humanized mice with a random virus,” he wrote on X. “Conversely, I could see how such stuff might go wrong…”

But despite the controversy and potential risks, it is not just Chinese scientists who are poking and prodding at coronavirus strains in a bid to better understand them.

With the worst days of the pandemic behind us, there has been a boom in research dedicated to genetically modifying Covid variants, cloning related pathogens, virus-hunting, and more.

Although some of it is happening in the east, much of the work is taking place in the UK, led by some of the biggest names in virology, as well as Germany, Switzerland, Japan, and the US.

The scientists involved insist there is little to fear and much to gain.

They say the experiments, conducted in safe, high-security laboratories, are essential for a better understanding of Sars-CoV-2 and the wider coronavirus family to which it belongs.

‘Reverse genetics’

A body called the G2P2-UK Consortium is leading this research in the UK.

Funded by the British taxpayer and run out of Imperial College in London, it was established with the aim of examining how current and emerging Covid variants are adapting in humans, and the means by which they come to take over in a population.

It also seeks to determine the role that different mutations – random changes in the genetic sequence of a virus – have on a variant’s characteristics, in terms of its lethality, transmissibility, and ability to escape vaccine-induced immunity.

“To understand why different variants of concern behave differently, we need to identify which mutations in the genome confer these properties,” said Professor Wendy Barclay, head of the G2P2 Consortium.

This process typically begins with the emergence of a new Covid variant that has acquired an array of mutations.

Those mutations which haven’t been seen before will take centre stage in the experiments that follow. Their genetic coding will be removed from the Covid strain under investigation and inserted into either the original Wuhan virus that emerged in late 2019 or, sometimes, another variant of concern.

This process – called ‘reverse genetics’ – changes the proteins of the virus that are responsible for its ability to, say, infect and replicate within human nasal cells, or its ability to dodge antibodies and other human defence mechanisms.

This modified virus will then be exposed to human cells grown in the lab or in hamsters to see whether such functions are heightened or diminished.

By repeatedly ‘mixing and matching’ different mutations through these experiments, scientists “can narrow down” which mutations are driving the variant’s troublesome characteristics, said Professor Stuart Neil, a virologist at King’s College London.

“You can break it down to a single point mutation or a group of mutations.”

Prof Barclay said the work has been vital in answering many of the unknown questions that had surrounded Sars-CoV-2 during the acute phase of the pandemic.

“For example, the original Covid virus replicates less efficiently in human nasal cells in the laboratory than Omicron and its sub-variants,” she said. “Why is that? Which ‘bits’ of the virus are responsible for this property?

“We can now say that these differences are due to the spike protein and in future we can look out for mutations that can affect this property and warn public health officials if needed.”

At first glance, the work appears to venture into the sort of genetic territory that enhances the characteristics of Sars-CoV-2 – a feature of so-called “gain-of-function” research.

Yet there’s a crucial difference: the scientists at the consortium aren’t adding any mutations to the virus that it hasn’t already learnt in the wild.

“We limit our studies to naturally occurring mutations that are already in the human population, we are not giving the virus any function it didn’t already have,” said Prof Barclay.

This differs from gain of function experiments which, for example, might fuse together the worst properties of two different viruses and see what risk this ‘chimera’ pathogen poses to humans.

Although the G2P2-UK’ Consortium isn’t conducting research of this high-risk nature, and nor are the Chinese virologists in Beijing, it makes sure to follow the strictest of safety protocols when running its own ‘mixing and matching’ experiments.

All projects begin with a written risk assessment that requires sign-off from the Health and Safety Executive (HSE), the UK’s workplace safety regulator. If the research is deemed too dangerous, authorisation won’t be granted.

Experiments involving the Covid virus and its variants are meanwhile performed in a ‘Containment Level 3’ laboratory – this is an airtight, gas-tight facility that uses specialised airflow design to prevent the escape of hazardous pathogens.

It’s one tier down from the top level of lab biosafety, CL4, in which the world’s deadliest diseases – from ebola to smallpox – are handled.

These facilities and their staff, who are specifically trained to operate in a CL3 lab, are audited at least once a year by the HSE – though a Telegraph investigation revealed earlier this year that recorded lab leaks and accidents have risen by 50 per cent in Britain since Covid emerged.

It’s understood that safety guidelines for laboratory experiments on the Covid-19 virus – including the swapping of mutations between variants – are being reviewed by HSE.

Regulations for sampling, testing and analysing Sars-CoV-2 were quickly implemented at the start of the pandemic but have never been updated.

Scientific understanding of “what makes the virus tick” has improved drastically since 2020, said one expert involved in the review, raising questions of whether laboratory protocols for the pathogen need to be strengthened – or relaxed.

A HSE spokesperson said: “As scientific knowledge on coronaviruses has now significantly improved, we’d like to know whether further risk assessment advice for genetically modifying coronaviruses would benefit the scientific community. This scoping exercise is ongoing.”

Risks, of course, will always persist in this line of work – especially when dealing with the unpredictability of constantly evolving viruses.

Yet it’s worth the reward of furthering our scientific understanding and, with it, improving humanity’s preparedness against future biological threats, argues Dr Benjamin Neuman, a virologist at Texas A&M University.

“Preparedness requires a certain amount of bravery, individually for the scientist, and collectively for society,” he said. “But preparedness saves lives.”

Source: The hidden portion of the article.

The article was from 13 February 2024 • 2:50pm. The only information that you can see are the pictures contained in the article. The text has been hidden.

So let me put the pieces of this puzzle together.

China began experimenting with modifying genes. The origins of the COVID pandemic was in China (and if I am not mistaken) originated from a research lab called Wuhan Institute of Virology. They were conducting experiments at this lab and created a virus called COVID. Elements from one virus was combined with another and a man-made virus developed. But it was very deadly and highly contagious and escaped from the lab. This quickly spread around the world and caused an estimated 7,003,621 deaths worldwide. This plague was highly contagious and it is estimated that 674,798,768 people had been infected with this diseases.

WorldOMeter

The true numbers will never be known. Some countries such as China, hid the true numbers especially during the beginning of the pandemic when the contagion was extremely deadly. This was an experiment gone wrong.

But what this encoded message that I came across indicated is that CHINA is still continuing on with exploring and creating new plagues. One of which is called the GX_P2V virus. Scientist have developed mice with human cells for experimentation. These are called Humanized Mice.

One website defines these cells as follows: How Humanized Mice are Created
The NCG model's immune system is humanized by irradiating and destroying the host immune system. Once the immune system is knocked out, human peripheral blood mononuclear cells (PBMCs) are injected to create a humanized model. Engrafted human cells can be detected as early as 10 days after the PBMC injection.

Maybe a better description of Humanized Mice is Half Human/Half Mice.

So a man made disease such as GX_P2V can produce a 100 percent fatality rate of Humanized Mice. I wonder what the fatality rate of this man made virus might be on HUMANS?

The cited article says: "a group of virologists from Beijing cloned and mutated a Covid-like virus found many years ago in a pangolin and used it to infect ‘humanised’ mice."

This is probably not the only human created virus/bacteria/fungus diseases that China is playing with.

Last edited by jimmy m on 04 Mar 2024, 12:35 pm, edited 3 times in total.

We all live in a yellow submarine - and there was me thinking I lived on planet Earth.

An article published in Nature Microbiology describes the research in China developing human variants of a virus from Pangolins. It reads:

Pangolins are the most trafficked wild animal in the world according to the World Wildlife Fund. The discovery of SARS-CoV-2-related coronaviruses in Malayan pangolins has piqued interest in the viromes of these wild, scaly-skinned mammals. We sequenced the viromes of 161 pangolins that were smuggled into China and assembled 28 vertebrate-associated viruses, 21 of which have not been previously reported in vertebrates. We named 16 members of Hunnivirus, Pestivirus and Copiparvovirus pangolin-associated viruses. We report that the l-protein has been lost from all hunniviruses identified in pangolins. Sequences of four human-associated viruses were detected in pangolin viromes, including respiratory syncytial virus, Orthopneumovirus, Rotavirus A and Mammalian orthoreovirus. The genomic sequences of five mammal-associated and three tick-associated viruses were also present. Notably, a coronavirus related to HKU4-CoV, which was originally found in bats, was identified. The presence of these viruses in smuggled pangolins identifies these mammals as a potential source of emergent pathogenic viruses.

Source: Trafficked Malayan pangolins contain viral pathogens of humans

Another article does a deep dive into the origin of COVID.

After the recent emergence of SARS-CoV-2 infection, unanswered questions remain related to its evolutionary history, path of transmission or divergence and role of recombination. There is emerging evidence on amino acid substitutions occurring in key residues of the receptor-binding domain of the spike glycoprotein in coronavirus isolates from bat and pangolins. In this article, we summarize our current knowledge on the origin of SARS-CoV-2. We also analyze the host ACE2-interacting residues of the receptor-binding domain of spike glycoprotein in SARS-CoV-2 isolates from bats, and compare it to pangolin SARS-CoV-2 isolates collected from Guangdong province (GD Pangolin-CoV) and Guangxi autonomous regions (GX Pangolin-CoV) of South China. Based on our comparative analysis, we support the view that the Guangdong Pangolins are the intermediate hosts that adapted the SARS-CoV-2 and represented a significant evolutionary link in the path of transmission of SARS-CoV-2 virus. We also discuss the role of intermediate hosts in the origin of Omicron.

Source: Role of the Pangolin in Origin of SARS-CoV-2: An Evolutionary Perspective

I came across another article discussing China's experimenting with GX_P2V.

Scientists in China have recently conducted experiments on a novel coronavirus strain, GX_P2V. It resulted in a 100% fatality rate in genetically-modified mice. This strain is a mutation of GX/2017, a virus initially identified in Malaysian pangolins in 2017.

The study, originating from Beijing, notes the swift and lethal impact of GX_P2V on mice with human-like genetic structures. The virus, targetting multiple organs including the brain, led to rapid deterioration in the mice's condition, culminating in death within eight days.

The mice got very sick quickly. They lost a lot of weight, couldn't move well, and their eyes turned white before they died. This study is different because all the mice died, which is more than what happened in other studies about similar viruses.

“SARS-CoV-2-related pangolin coronavirus GX_P2V(short_3UTR) can cause 100% mortality in human ACE2-transgenic mice, potentially attributable to late-stage brain infection. This underscores a spillover risk of GX_P2V into humans and provides a unique model for understanding the pathogenic mechanisms of SARS-CoV-2-related viruses," wrote the authors.

This study is separate from the research in Wuhan, which was linked to different ideas about where COVID-19 came from. The origin of COVID-19 is still not known. The new study in China raises questions about doing risky experiments with viruses.

Source: A new study in China raises questions about risky experiments with viruses as scientists conducted experiments on a novel coronavirus strain resulting in a 100% fatality rate in genetically-modified mice.

Is this part of their bio-weapons research? They certainly managed to avoid global sanctions the first time it was released.

That is a very good question. Are some individuals plotting the extinction of the human race. There was a group about 20 years ago who believed the world was overpopulated. They formed a very detailed hidden society. I remember a movie that contained their core thoughts.

The world is coming to an end. Keep it secret from the rest of the world. Take all your wealth (these were the elites with vast wealth). Build special ships to survive the carnage. And that is what they did. It was an End of the World scenario.

This movie was not a 1998 film called Armageddon or another film called Deep Impact. Rather this film was a film from 2009 called 2012. It was an American science fiction disaster film.



The elites of the world used all their wealth to ensure their survival. But they left everyone else in the dark until it was too late.



One website provides some insight into the plot of this film.

2012

In 2009, American geologist Adrian Helmsley visits astrophysicist Satnam Tsurutani in East India and learns that a new type of neutrino from a solar flare is heating the Earth's core. Returning to Washington, D.C., Adrian alerts White House Chief of Staff Carl Anheuser and President Thomas Wilson.

In 2010, over forty-six nations begin building nine arks in the Himalayas, in Tibet, and storing artifacts in secure locations. Nima, a Buddhist monk, is evacuated with his grandparents, and his brother Tenzin joins the ark project. Additional funding is secretly raised by selling tickets to the rich for €1 billion per person.

In 2012, struggling science-fiction writer Jackson Curtis is a chauffeur in Los Angeles for Russian billionaire Yuri Karpov. Jackson's former wife Kate and their children, Noah and Lilly, live with Kate's boyfriend, plastic surgeon and amateur pilot Gordon Silberman. Jackson takes Noah and Lilly camping in Yellowstone National Park. When they find Yellowstone Lake dried up and fenced off by the United States Army, they are caught and brought to Adrian. They later meet conspiracy theorist and radio personality Charlie Frost, who tells Jackson of Charles Hapgood's earth crust displacement theory and the Mesoamerican Long Count calendar predict the end of world in 2012 and worldwide catastrophe, and that the world's governments silence anyone attempting to warn the public.

The plot goes on and on but the pending doom is held secret from the world.

Many years ago, around age 20, I was about to be drafted to fight in the Vietnam War. But I chose a different direction and was able to get into the Air National Guards. As a result, I received training in Boot Camp and Tech School for about a half a year and then served my military obligation for a total of 6 years. During Boot Camp, I received a series of vaccinations. Most of the shots were mild and had little to no effect. But one shot was extreme. It was a shot to protect me from the Black Plague. For 15 minutes after getting the shot, I stood at attention, but I could feel the effect of this vaccine. I almost fainted. Many of the young soldiers in my group also felt the severity of this vaccine. They fell to the ground and I could hear their skulls hitting the concrete pavement below. It was the most severe vaccine I ever received and I still remember it 55 years later.

It gave me a full understanding of how severe the Black Plague must have been.

Now it seems like perhaps this plague is returning, compliments of China. One recent article provides some insight.

The emergence of two cases of bubonic plague in Inner Mongolia, China, serves as a striking reminder of the persistent threat posed by this ancient and enigmatic infectious disease. Bubonic plague, infamous for its historical devastation during the Middle Ages as the ‘Black Death’, has reappeared in the modern world, prompting renewed concerns over its potential to cause significant health impacts. The recent cases reported from Inner Mongolia underscore the necessity of understanding the historical context, causative agent, transmission dynamics, clinical manifestations, and contemporary implications of this formidable pathogen. The bubonic plague has left an indelible mark on human civilization, claiming millions of lives across continents. The disease’s rapid and often fatal course, characterized by painful swelling of lymph nodes and high fever, has left an enduring legacy of fear and fascination. Yersinia pestis, the bacterium responsible for bubonic plague, has maintained its presence in various parts of the world, continuing to wreak havoc on human and animal populations.

On 7 August 2023, a bubonic plague infection was recorded in the Inner Mongolia region. Within 4 days, on 11 August, two new cases emerged: the husband and daughter of the index patient. The unusual occurrence of human-to-human transmission of bubonic plague suggests a common source for these infections. This underscores the imperative of swiftly identifying the outbreak’s source to preempt further instances.

Source: Correspondence Alert from Inner Mongolia: two bubonic plague cases reported in China

The Black Death was a bubonic plague pandemic occurring in Europe from 1346 to 1353. One of the most fatal pandemics in human history, as many as 50 million people perished, perhaps 50% of Europe's 14th century population. Bubonic plague is caused by the bacterium Yersinia pestis.

Source: Black Plague