So the principle of the candida diet was right after all...

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They've discovered Clostridium bolteae as the cause of the modern ASD epidemic and the substance it s**ts into your gut/blood "propionic acid" is responsible for the symptoms/behaviors of ASD's.

Genetic research has shown ASD's are epigenetic and not genetic there is no autism gene, genetic causes of autism only represent a very small amount of the autistic population (5-10%). So all these no hope autism nazi's with a superiority complex (believing autism is the cure to the world) are welcome to [mod. edit: sexual reference redacted]. Genetic research shows evidence against autism being genetic if anything. There is no autism gene rather a pattern of normal genes that just seem to show up more apparent in autism, meaning genetics are not causing these symptoms. autism is epigenetic, anyway more onto solid science.

Candida was the disease everyone thought was nonsense (me too and I actually have candida overgrowth). It's been shown the autistic population does have vastly more intestinal candida as compared to the normal population. But it doesn't cause autism or really have anything to do with it besides coexisting with autism.
The theory (science actually) behind the diet is that candida itself plants itself in the intestinal mucosa and eats all the carbs/sugar, converts them into methyl-alcohol and s**ts this into your bloodstream along with 79 other neurotoxins.

Now it's the exact same theory except with bad bacteria (which the candida diet also helps rebalance) the Clostridium bolteae converts foods into prepionic acid and s**ts this into your gut and your gut absorbs it like food, they have now deemed this as the main cause of ASD's. Its like drinking poison except you're always drinking it.

Now my question is how many other strains of bacteria (there a trillions) are there that exist in the autistic gut producing god knows how many pathogens like the prepionic acid (as the research is still very new).

Vaccines/metals/mercury/gluten/casein/glutathione it's not one or the other they're all linked. I'm not going to write an essay on how the immune system works as I wouldn't know in its entirety however it all these things can fall under the banner of mitochondria dysfunction and oxidative stress/poor methylaton.

I remember arguing on here years ago regarding mercury and metals as all the studies up to then weren't credible and showed no links to autism. This was because the ignorant researchers never chelated the patients before taking the blood samples. This means the metal isn't mobilized and makes a blood test (and most others) unreliable. Here's a link to the first autism-metal test that wasn't performed with negligence (ie they used DMSA to chelate, and not thin air) http://www.sciencedaily.com/releases/20 ... 162231.htm

Last edited by jametto on 01 May 2013, 1:54 pm, edited 2 times in total.

I think you are overstating the case for a Clostridium boltae and autism link. The researchers themselves are looking into whether it could be a contributing or even causative factor in some cases. The results are mixed and some replications of the original study have shown more C.boltae in some autistic children whereas others have not.

An article on this:

http://crackingtheenigma.blogspot.com/2 ... nigma.html

some excerpts: Tested autistic kids were given vancomycin, an antibiotic which would kill the C. boltae. Whether or not their autistic symptoms improved any is entirely subjective.

Verified repeatable only once. And another followup study didn't repeat the results.



So it's really too soon to leap to any conclusions.

I won't address the OP's non-research related rants because I figure somebody else will do that and better than me.

Mine is definitely genetic. I have two children with it, and a sister with schizophrenia which is genetically related. I also believe my dad had it. They also have identified some autistic genes, so it's not true that none have been discovered.

Your post could have done without the vile swearwords OP.

Where's the evidence? Until researchers actually examine intestinal microflora and serum propionic acid levels and publish the results then this is just another theory to add to the countless others about the etiology of autism.

Researchers did do that (see my post upthread) but the results have been inconsistent.

These studies are generally related to the etiology of gastrointestinal disorders in autistic people, rather than the etiology of autism itself.

They are not suggesting a causal relationship between gastrointestinal microflora and autism.

No. The studies were on intestinal microflora but not on gastrointestinal disorders. They were very specifically trying to find a relationship between intestinal microflora and autistic behaviour. Whether they found it or not was not clear but they weren't investigating gastrointestinal disorders

http://crackingtheenigma.blogspot.com/2 ... nigma.html

Last edited by Janissy on 01 May 2013, 2:06 pm, edited 1 time in total.

Quite a few papers and the context is always the higher prevalence of gastrointestinal disorders in autistic people, e.g.

Differences between the gut microflora of children with autistic spectrum disorders and that of healthy children, 10.1099/jmm.0.46101-0 J Med Microbiol October 2005 vol. 54 no. 10 987-991 http://jmm.sgmjournals.org/content/54/10/987.long

"Children with autistic spectrum disorders (ASDs) tend to suffer from severe gastrointestinal problems. Such symptoms may be due to a disruption of the indigenous gut flora promoting the overgrowth of potentially pathogenic micro-organisms.[...] Strategies to reduce clostridial population levels harboured by ASD patients or to improve their gut microflora profile through dietary modulation may help to alleviate gut disorders common in such patients. "

You're right that some researchers are also looking at how the microflora influences autism symptoms, but no causal relationship has been established at the studies have generally been very small scale.

Do you have any scientific links to support this?

From http://www.sci-news.com/medicine/article01038.html,

Note that "some researchers" believe that it may be related to the "symptoms and severity of autism". That isn't the same as saying it is a cause of autism. As usual, more research is necessary.

If you have any links to reputable scientific sources, especially peer reviewed journals, that report on studies that find a causal link, we would all be interested.

A lot of my anxiety issues have seriously improved after I managed to get rid of a lot of candida I had in me during the last months using certain rituals.

It made me feel lighter and more mobile.

And I notice that candida, anxiety, chronic fatigue syndrome and food allergies are also quite connected to eachother more than you would actually think.

There are studies that show proof of a gut-brain connection. I'd call this autism but that depends on what you call autism as it really has no unique symptom, but a collection of symptoms that exist in other disorders. The labels don't really make sense to me anymore and overlap.. it's portrayed as though these symptoms are exclusive to autism whereas they can all be seen mainly in anxiety and stress disorders.
I remember trying to find the difference between aspergers and Social Anxiety Disorder and it was defined as all the behaviors in group (A) of the Aspergers DSM-IV not applying to SAD. Such as facial expression, eye contact, body language, empathy deficits etc which is a joke as they're all prevalent in social anxiety disorder let alone many other disorders.

Anyway research shows the gut-brain connection and how bacteria can cause anxiety "like" symptoms/mood and behavioral issues by interacting with neurons, and how they can alter brain deveopment/wiring.

http://www.ncbi.nlm.nih.gov/pubmed/19210574
http://www.ncbi.nlm.nih.gov/pubmed/22638926
http://www.endonurse.com/news/2011/03/r ... -mind.aspx

I wonder what's left autism wise in an individual once all these pathogens are eradicated?? and how many other underlying immune factors still remain that are causing negative symptoms (google pyroluria for one). It's looking to be more along the lines of a illness/disease rather than a disorder. Once all this crap is fixed you could be left with an overly wired brain which may not be such a bad thing. and could even rewire itself maybe as it's no longer chronically exposed to pathogens every second of everyday of your entire life. It's a nice thought lol

I've many times taken a variety of probiotics and prebiotics, in live form and tablet form. It's never made any difference. I also tried high dose vitamin D which made no difference.

Eradication of pathogens and environmental toxins would benefit anyone, autistic or not.

I must admit that I'm confused by the theory referenced in the OP.

If the theory about some sort of negative reaction caused by the digestive tract is true, then how does one get this particular combination of digestive tract issues? Are there any other people out there with these digestive tract issues that are not showing up with an ASD Dx?

Same goes for me! My anxiety has improved dramatically I do not zone out when off gluten and dairy that's something massive I've noticed as well as meltdown like feelings. Sugar makes me very dizzy/brain foggy but then again I can't seem to shake that feeling ever, its that light dizzy dopey feeling. People have mentioned I'm a lot more "there" when off these foods. I can't stay on the candida diet for more than 2-3 days though lol I always end up binging on chocolate and ice cream, then feel horrid and throw it up lol reminding myself why I shouldn't eat it, but I always go back!

There's millions people with gut disorders there is no straight answer. It's too complicated for me to explain really someone else could but do some research and you'll find gut disorders are not exclusive to autism. Then autism is also spectrum disorder, like schizophrenia which is proposed to have the exact same mechanism on an even larger scale (however more oxidative stress prominent than gut related).http://www.sciencedaily.com/releases/20 ... 102107.htm

A rigid method of deduction cannot apply. For example Clostridium Bolteae secretes priopionic acid, Candida albicans secretes methyl-alcohol. Both create gut imbalance issues yet express themselves differently due to two completely different chemical compounds causing their relative symptoms. Thats only 2 microbes and there are trillions, they would affect everyones personality make them who they are, maybe that's the secret to life, people are just millions of bacteria lol.

But to answer your question as best as I can the normal population does not host Clostridium Bolteae whereas the autistic population does as well as other biomakers being evident of other pathogens in urine of patients with ASD's. Why Clostridium Bolteae survives in the autistic GI tract and not the normal population is very interesting and unknown.

Gut imbalance is the answer obviously and bad diet/mercury poisoning/allergies and other things contribute to this I'm sure all this sounds familiar lol, mmr vaccines/amalgam fillings and whatnot. Oxidative stress/and a form mitocondria dysfunction (metabolic cells get stuck in defense mode) is the word they're using for it now as they've all been linked to autism (mercury too finally after so much controversy).

The genetic factor of autism could be glutathione deficiency. The bodys critical antioxidant that flushes out toxins/metals etc and by toxins that includes all the gut bacteria, anything really as this applies to everyone, theoretically then someone with this form of autism should be more affected by intoxication in general ie smoking cigarettes, drinking, living in the city, and especially from foods (due to bad bacteria in autistics converting this into toxins like the propionic acid that wouldn't occur in normal people and recovering from illnesses (herxheimer reaction ontop of passive gut induced herxheimer) and the devastating consequence this has on the body of this results in autism.

I could go on all day as the propionic acid and other pathogens can induce oxidative stress from overloading the body with toxins, but inherited oxidative stress (glutathione deficiency) predisposes the person to heavy metals (toxins themselves that use up more glutathione) and this results in the gut imbalance anyway (mercury sparks candida which sparks bacterial imbalance which secrete more toxins causing yet even further oxidative stress). The immune system is screwed basically double edged swords all over the place.
This is why autistic people have dark circles around their eyes as well as many other people, it's a known biomarker of oxidative stress, I simply cannot get rid of mine and they're a lot worse now than they were before my gut became extremely bad it's definitely related. Doesn't seem to matter what diet I go on or how many toxins I cut back on consuming as the dark circles never change! When they're gone I'll evaluate myself to see how autistic I am because part of the disorder or not oxidative stress is a illness.
Here's some very informative reads

http://www.sciencedaily.com/releases/20 ... 182019.htm
http://www.sciencedaily.com/releases/20 ... 162231.htm
http://www.sciencedaily.com/releases/20 ... 102107.htm